Lymphatic drainage of the breast on and through the pectoral muscles: Importance in breast cancer
โ Scribed by Robert L. Cucin; Dr. Randolph H. Guthrie; Eleanor E. Deshner
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 259 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0008-543X
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โฆ Synopsis
As proponents of lesser procedures have called into question the necessity of removing the pectoral muscles in surgery for cancer of the breast, there has been a need to establish accurately the relationship of the lymphatics to the pectoral muscles and their fascia. This problem has been approached using the technique of high resolution autoradiography. After histologic review of pectoral muscles from rabbits into whom a tritiated high-molecular-weight dextran was injected subareolarly, a high degree of labeling was found deep within the septa of the pectoral muscle bundles as well as along the investing fascia. It was concluded that lymphatic draining mammary lymph pass deep within the pectoral muscles in this species.
๐ SIMILAR VOLUMES
Recent in vitro and animal tumor studies suggest that sequential methotrexate (MTX) and 5-fluorouracil (5-FU) may be much more tumoricidal than either drug when used alone or in conventional combinations. Seventeen evaluable female patients with advanced carcinoma of the breast were treated with MTX