Lymph nodes in incipient adult T-cell leukemia-lymphoma with Hodgkin's disease-like histologic features

Clonal HTLV-I-infected CD4+ T-lymphocyte

Clonal HTLV-I-infected CD4+ T-lymphocytes and non-clonal non-HTLV-I-infected giant cells in incipient ATLL with Hodgkin-like histologic features

✍ Koichi Ohshima; Junji Suzumiya; Akiko Kato; Kohtaro Tashiro; Masahiro Kikuchi 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 278 KB

Lymph nodes from the incipient or early neoplastic phase of adult T-cell leukemia/lymphoma (ATLL) histologically resemble Hodgkin's disease. Integrated proviral human Tlymphotrophic virus type I (HTLV-I) has been demonstrated in such lesions. We studied 18 patients with this disease, and about half