Autocrine IL-10 impairs dendritic cell (
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Caroline Demangel; Patrick Bertolino; WarwickβJ. Britton
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Article
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2002
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John Wiley and Sons
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English
β 137 KB
The production of IL-12 by dendritic cells (DC) early in an immune response is considered critical for the polarization of CD4 + T lymphocyte response towards a Th1 pattern, a key process in the clearance of intracellular pathogens. Infection of bone marrow-derived DC with Mycobacterium bovis Bacill