Lymph node invasion in hypopharynx and lateral epilarynx carcinoma: A prognostic factor

✍ Scribed by Lefebvre, J. L. ;Castelain, B. ;De Torre, J. C. La ;Delobelle-Deroide, A. ;Vankemmel, B.

• Book ID: 102236110
• Publisher: Wiley (John Wiley & Sons)
• Year: 1987
• Weight: 384 KB
• Volume: 10
• Category: Article
• ISSN: 0148-6403
• DOI: 10.1002/hed.2890100104

✦ Synopsis

Hypopharynx (HC: pyriform fossa, postcricoid area, and posterior wall) and lateral epilarynx carcinomas (LEC: aryepiglottic fold, pharyngoepiglottic fold, and arytenoid) have a high tendency to cervical lymph node invasion. Such nodal extension is a well-known prognostic factor. This study is based on a retrospective review of 884 clinical records of previously untreated HC or LEC. Seventy percent of patients revealed palpable nodes at their first examination, with a higher percentage for HC (73%) than LEC (62%). The 5-year survival rate was divided by three in the presence of contralateral, bilateral, or fixed nodes, or in cases of nodes exceeding 3 cm. Multiple positive nodes, extracapsular spread, or lower-neck positive nodes significantly decreased survival, doubled the number of neck recurrences, and tripled the number of distant metastases while control at the primary site remained unvaried. HEAD & NECK SURGERY 10:14-18,1987 Hypopharynx (HC: pyriform fossa, postcricoid area, and posterior wall) and lateral epilarynx carcinomas (LEC: aryepiglottic fold, pharyngoepiglottic fold, and arytenoid) have remarkably poor prognoses regarding survival rates and loco-From the ENT and Head & Neck Oncology Department (Drs Lefebvre,