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Lymph node imprint cytology for the rapid assessment of axillary node metastases in breast cancer

✍ Scribed by D. S. Quill; A. L. Leahy; R. G. Lawler; R. D. Finney

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 173 KB
Volume: 71
Category: Article
ISSN: 0007-1323
DOI: 10.1002/bjs.1800710616

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✦ Synopsis

Lymph node imprint cytology for the rapid assessment of axillary node metastases in breast cancer

Lymph node imprint cytology was performed on 86 nodes from 13 consecutive patients with breast cancer undergoing simple mastectomy with axillary node sampling, and a prospective comparison with parafin section was made. The results showed a diagnostic sensitivity and specificity oJ'0.93 and 0.98 respectively. The predictive value of a positive result was 0.98. This technique can be used to identfy patients with Stuge I disease rapidly, therebjJ allowing their exclusion from treatment with peri-operative chemotherapy.

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## Abstract ## Background Intraoperative diagnosis of sentinel node metastases enables an immediate decision to proceed to axillary lymph node dissection, avoiding a second operation in node-positive women with breast cancer. ## Methods An optical scanner was developed that interrogated the cut