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Lymph node aspiration biopsy diagnostic reliability and limitations—an analysis of 350 cases

✍ Scribed by Ibrahim Ramzy; Rene Rone; Stephen J. Schul Tenover; James Buhaug

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
510 KB
Volume
1
Category
Article
ISSN
8755-1039

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✦ Synopsis

The results offine needle aspiration biopsy

of lymph nodes in 350 patients and the modified biopsy technique used at our institution are discussed. Of the 350 cases, 209 aspirates were categorized as cytologically malignant, 102 as benign, 30 as suspicious for malignancy, and 9 as unsatisfactory. Cervical lymph nodes were most commonly sampled (58 % ), and supraclavicular nodes were most likely to be malignant (90%). The overall diagnostic accuracy achieved was 94 9%. One falsepositive and 9 ( 2 % ) false-negative results were observed in the 350 cases. In 3% of the 30 cases diagnosed as suspicious for malignancy, follow-up open biopsy of the lymph nodes in question proved them benign. The advantages and limitations ofthe procedure are discussed, 0s well as some of the possible sources of error, particularly in the diagnosis of lymphomas.

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