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Lycopene regulation of cholesterol synthesis and efflux in human macrophages

✍ Scribed by Paola Palozza; Rossella Simone; Assunta Catalano; Nadia Parrone; Giovanni Monego; Franco O. Ranelletti

Book ID
113731977
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
965 KB
Volume
22
Category
Article
ISSN
0955-2863

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## Abstract Altered lipid metabolism has been implicated as a critical player in osteoarthritis (OA). Our study aimed to investigate the expression of genes regulating cholesterol efflux in human chondrocytes and to study the effect of an LXR agonist on cholesterol efflux and lipid accumulation in