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Lycopene differentially induces quiescence and apoptosis in androgen-responsive and -independent prostate cancer cell lines

✍ Scribed by Nikita I. Ivanov; Simon P. Cowell; Paula Brown; Paul S. Rennie; Emma S. Guns; Michael E. Cox


Book ID
113545271
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
512 KB
Volume
26
Category
Article
ISSN
0261-5614

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Progression to androgen independence remains the main problem that impacts on survival and quality of life in prostate cancer patients. We have investigated the potency of tributyrin, an orally available prodrug of butyrate, to induce growth arrest, differentiation and apoptosis in LNCaP, PC-3 and T