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Ly-5 (T200) structural polymorphism: The identification of intramolecular sites of phosphorylation

✍ Scribed by Andrew J. Watson

Publisher: Springer-Verlag
Year: 1982
Tongue: English
Weight: 383 KB
Volume: 16
Category: Article
ISSN: 0093-7711
DOI: 10.1007/bf00372106

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✦ Synopsis

The murine alloantigen Ly-5 is expressed as one of two alternative alleles on virtually all cells of hematopoetic lineage (Komuro et al. 1975, Scheid and Triglia 1979, Triglia 1980). At the molecular level, Ly-5 is synonymous with T200 and is a large transmembrane phosphorylated glycoprotein (Omary et al. 1980, Siadak andNowinski 1980). On lymphocytes, Ly-5 has been found to exist in a broad spectrum of molecular weight (mol. wt.) forms; the mol. wt. forms observed apparently reflect to a great extent the differentiational status of the expressing lymphocyte population (Omary

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