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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

✍ Scribed by Laffitte, B. A.; Repa, J. J.; Joseph, S. B.; Wilpitz, D. C.; Kast, H. R.; Mangelsdorf, D. J.; Tontonoz, P.

Book ID
121753109
Publisher
National Academy of Sciences
Year
2001
Tongue
English
Weight
413 KB
Volume
98
Category
Article
ISSN
0027-8424

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## Abstract Apolipoprotein E (apoE), a key regulator of lipid metabolism, is highly produced by adipose tissue and adipocytes. However, there is little information about its role on adipocyte functions. Because apoE‐deficiency in adipocytes was shown to impair adipocyte differentiation, we investig