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Luteinizing hormone-releasing factor increases release of human chorionic gonadotrophin in isolated cell columns of normal and malignant trophoblasts

✍ Scribed by R. Bützow

Publisher
John Wiley and Sons
Year
1982
Tongue
French
Weight
284 KB
Volume
29
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

The effect of synthetic luteinizing hormone‐releasing factor (LRF) on release of human chorionic gonadotrophin (hCG) was studied by isolated cell columns of normal syncytiotrophoblasts and choriocarcinoma (BeWo) cells. After LRF stimulation the release of hCG by the normal trophoblasts increased up to 4‐fold and release by the malignant trophoblasts increased up to 6‐fold, indicating a specific effect of LRF on normal and malignant trophoblast cells.

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