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Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn

✍ Scribed by Calvin C.K. Yu; T.S.Benedict Yen; Clifford A. Lowell; Anthony L. DeFranco

Book ID
114317265
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
265 KB
Volume
11
Category
Article
ISSN
0960-9822

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## Abstract We have investigated the contribution of Hck, Lyn and Fgr, highly expressed Src family tyrosine kinases (SFKs) in signalling pathways in opsonized zymosan (OZ)‐activated phagocytes by using short interfering RNAs (siRNAs). Treatment of macrophage‐like U937 cells with the siRNAs targeted