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Lupus-inducing drugs alter the structure of supercoiled circular dna domains

✍ Scribed by Wolfgang Zacharias; William J. Koopman


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
848 KB
Volume
33
Category
Article
ISSN
0004-3591

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## Abstract DNA of higher eukaryotes is organized in supercoiled loops anchored to a nuclear matrix (NM). The DNA loops are attached to the NM by means of non‐coding sequences known as matrix attachment regions (MARs). Attachments to the NM can be subdivided in transient and permanent, the second t