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Lunx Is a Superior Molecular Marker for Detection of Non-Small Lung Cell Cancer in Peripheral Blood

✍ Scribed by Mitas, Michael; Hoover, Loretta; Silvestri, Gerard; Reed, Carolyn; Green, Mark; Turrisi, Andrew T.; Sherman, Carol; Mikhitarian, Kaidi; Cole, David J.; Block, Mark I.; Gillanders, William E.


Book ID
121435458
Publisher
American Society for Investigative Pathology
Year
2003
Tongue
English
Weight
178 KB
Volume
5
Category
Article
ISSN
1525-1578

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## Abstract Aberrant methylation of several tumor suppressor genes often occurs during the pathogenesis of lung cancer. RASSF1A is one of the tumor suppressor genes, and it is frequently inactivated by hypermethylation of its promoter region in a variety of human cancers, including lung cancer. It