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Lung carcinoma induction in BD rats after a single intratracheal instillation of an arsenic-containing pesticide mixture formerly used in vineyards

✍ Scribed by S. Ivankovic; G. Eisenbrand; R. Preussmann


Publisher
John Wiley and Sons
Year
1979
Tongue
French
Weight
658 KB
Volume
24
Category
Article
ISSN
0020-7136

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✦ Synopsis


Abstract

A single intratracheal 0.1‐ml instillation of a calcium‐arsenate containing vineyard pesticide induced multi‐focal bronchogenic adenocarcinomas and bronchiolar‐alveolar‐cell carcinomas in nine out of 15 treated BD rats. This seems to be the first experimental confirmation of carcinogenicity of arsenic‐containing pesticides used formerly in vineyards.