𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Lung carcinoma in former smokers

✍ Scribed by Longzheng Tong; Margaret R. Spitz; John J. Fueger; Christopher I. Amos


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
588 KB
Volume
78
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

✦ Synopsis


BACKGROUND.

A reduction in the risk of lung carcinonia and a lower death rate among former smokers (FS) compared with current smokers (CS) have been documented in numlerous U.S. and international studies. The main objective of our study was to compare the differences in demographic and clinical characteristics in groups stratified by smoking status and gender to evaluate the effect of smoking history and cessation on age at lung carcinoma diagnosis and on specific histologic type.

METHODS.

We conducted a cross-sectional study of lung cancer at The University of Texas M. D. Anderson Cancer Center from January 1986 to December 1990 and from January 1992 to December 1993. This study included 1039 patients age 19-88 with confirmed primary lung carcinoma who responded to self-administered risk factor questionnaires. Among them, 497 patients (47.83%) were CS, 444 patients (42.73%) were FS, 98 patients (9.43%) had never smoked (NS), and 840 patients (80.8%) were heavy ;smokers (more than 20 pack-years).


πŸ“œ SIMILAR VOLUMES


Aberrant p16 promoter methylation in smo
✍ Sonata Jarmalaite; Annamaria Kannio; Sisko Anttila; Juozas R. Lazutka; Kirsti Hu πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 128 KB

Hypermethylation of cytosines in CpG-rich islands of the promoter regions of regulatory genes has been discovered as a common mechanism of gene silencing during carcinogenesis. We analysed 64 primary lung carcinomas for promoter methylation of the tumour suppressor genes (TSGs) p16 (p16(INK4a)/CDKN2

Frequencies of hprt mutant lymphocytes i
✍ Marinel M. Ammenheuser; Darlene A. Hastings; Elbert B. Whorton Jr.; Jonathan B. πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 83 KB

Previous work with the autoradiographic mutant 21 former tobacco smokers had a mean variant lymphocyte assay has provided information about (mutant) frequency (Vf { standard error) of 1.97 the time-course of development of hprt mutations ({0.13) per million evaluatable cells. The Vf of and the persi

Beta-carotene in multivitamins and the p
✍ Tawee Tanvetyanon; Gerold Bepler πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 213 KB πŸ‘ 1 views

## Abstract ## BACKGROUND Some studies have suggested that beta‐carotene supplementation may increase the risk of lung cancer, particularly among smokers or former smokers. Beta‐carotene, a provitamin A, is available in multivitamins. In the current study, the authors investigated the risk of lung

Multiplicity of abnormal promoter methyl
✍ Kevin K. Divine; Leah C. Pulling; Patricia G. Marron-Terada; Kieu C. Liechty; Te πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 French βš– 126 KB

## Abstract The prevalence of methylation of the __p16, DAPK__ and __RASSF1A__ genes was investigated in lung adenocarcinoma from smokers, former uranium miners and never smokers. The association between a common genetic alteration in adenocarcinoma, mutation of the __K‐ras__ gene and methylation o

Physical activity and lung cancer risk i
✍ Lisa H. Colbert; Terryl J. Hartman; Joseph A. Tangrea; Pirjo Pietinen; Jarmo Vir πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 90 KB πŸ‘ 1 views

## Abstract We examined the association between physical activity and lung cancer in a prospective cohort of 27,087 male smokers, ages 50–69 years, enrolled in the Alpha‐Tocopherol, Beta Carotene Cancer Prevention (ATBC) Study. After an average of 10 years of follow‐up, 1,442 lung cancer cases were