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Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure

Book ID: 123431363
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 149 KB
Volume: 11
Category: Article
ISSN: 0169-5002
DOI: 10.1016/0169-5002(94)92188-1

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## Abstract Genetic backgrounds may modify the association of environmental tobacco smoke (ETS) with lung cancer risk. Polymorphisms of both the activating and detoxifying enzymes, cytochrome P4501A1 (CYP1A1) and glutathione‐S‐transferase M1 (GSTM1), may be important as genetic factors. We conducte