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Lung cancer and mesothelioma in towns with environmental exposure to asbestos in Eastern Anatolia

✍ Scribed by Hatice Canan Hasanoglu; Zeki Yildirim; Hilal Ermis; Talat Kilic; Nurhan Koksal

Book ID: 106102045
Publisher: Springer-Verlag
Year: 2005
Tongue: English
Weight: 228 KB
Volume: 79
Category: Article
ISSN: 0340-0131
DOI: 10.1007/s00420-005-0010-6

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## Abstract We investigated point mutational activation of the __ras__ genes (K‐__ras__ codons 12, 13 and 61; N‐__ras__ codons 12, 13 and 61; H‐__ras__ codons 12 and 61) in primary, resected lung cancer by dot blotting and oligonucleotide hybridization. K‐__ras__ mutations were found in 14 (29%) of