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Lubeluzole inhibits accumulation of extracellular glutamate in the hippocampus during transient global cerebral ischemia

✍ Scribed by Herbert Koinig; Vadim Vornik; Carlos Rueda; Mark H Zornow


Book ID
113996962
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
75 KB
Volume
898
Category
Article
ISSN
0006-8993

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## Abstract Using microdialysis in CA1 of the rat hippocampus, we studied the effect of transient cerebral ischemia on in vivo uptake and on extracellular levels of glutamate during, and at different time points after ischemia. ^3^H‐D‐aspartate (test substance), and ^14^C‐mannitol (reference substa