LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering β-catenin subcellular distribution

β-catenin mediates alteration in cell pr

β-catenin mediates alteration in cell proliferation, motility and invasion of prostate cancer cells by differential expression of E-cadherin and protein kinase D1

✍ Viqar Syed; Paul Mak; Cheng Du; K.C. Balaji 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 424 KB

## Abstract We have previously demonstrated that Protein Kinase D1 (PKD1) interacts with E‐cadherin and is associated with altered cell aggregation and motility in prostate cancer (PC). Because both PKD1 and E‐cadherin are known to be dysregulated in PC, in this study we investigated the functional