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LPS inhibits caspase 3-dependent apoptosis in RAW264.7 macrophages induced by the AMPK activator AICAR

✍ Scribed by Russe, Otto Quintus; Möser, Christine V.; Kynast, Katharina L.; King, Tanya S.; Olbrich, Katrin; Grösch, Sabine; Geisslinger, Gerd; Niederberger, Ellen


Book ID
122158696
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
519 KB
Volume
447
Category
Article
ISSN
0006-291X

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## Abstract A20 was originally characterized as a TNF‐inducible gene in human umbilical vein endothelial cells. As an NF‐κB target gene, A20 is also induced in many other cell types by a wide range of stimuli. Expression of A20 has been shown to protect from TNF‐induced apoptosis and also functions