LPA, HGF, and EGF utilize distinct combinations of signaling pathways to promote migration and invasion of MDA-MB-231 breast carcinoma cells

Glabridin, an isoflavan from licorice ro

Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway

✍ Ya-Ling Hsu; Ling-Yu Wu; Ming-Feng Hou; Eing-Mei Tsai; Jau-Nan Lee; Hsin-Lin Lia 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 405 KB

## Abstract **Scope:** In this study we first report the antimigration, antiinvasive effect of glabridin, a flavonoid obtained from licorice, in MDA‐MB‐231 human breast adenocarcinoma cells. **Methods and results:** Glabridin exhibited effective inhibition of cell metastasis by decreasing cancer c