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LOX-1 Mediates Redox-Sensitive, Akt/eNOS and Ca2+ Signaling Pathways Induced in Endothelial Cells by Monocyte Adhesion

✍ Scribed by Nobuo Sakamoto; Toshiyuki Ishibashi; Koichi Sugimoto; Hiroshi Ohkawara; Tatsuya Sawamura; Nobutaka Inoue; Yasuchika Takeishi

Book ID
116985790
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
47 KB
Volume
45
Category
Article
ISSN
0022-2828

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Role of LOX-1 in monocyte adhesion-trigg
Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+ signaling pathways in endothelial cells
✍ Nobuo Sakamoto; Toshiyuki Ishibashi; Koichi Sugimoto; Tatsuya Sawamura; Takayuki 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 574 KB

## Abstract This study was conducted to examine the role of lectin‐like oxidized low‐density lipoprotein receptor‐1 (LOX‐1) in monocyte adhesion‐induced redox‐sensitive, Akt/eNOS and Ca^2+^ signaling pathways in endothelial cells (ECs). LOX‐1 was blocked by an antibody‐neutralizing LOX‐1 TS92 or sm