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Lowered seizure threshold as a part of the narcotic abstinence syndrome in rats

✍ Scribed by M. W. Adler; C. Lin; K. P. Smith; R. Tresky; P. L. Gildenberg


Publisher
Springer
Year
1974
Tongue
English
Weight
298 KB
Volume
35
Category
Article
ISSN
0033-3158

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✦ Synopsis


A decrease in threshold to flurothyl-induced seizures in rats is a sensitive measure of the morphine primary abstinence syndrome. The test is easy to perform, yields highly reproducible results, allows for simple statistical group comparisons and correlates well with the usual methods of assessing withdrawal.


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