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Lower concentration of pulmonary hepatocyte growth factor is associated with more severe lung disease in preterm infants

✍ Scribed by Patrik Lassus; Päivi Heikkilä; Leif C Andersson; Kristina von Boguslawski; Sture Andersson


Book ID
117849834
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
115 KB
Volume
143
Category
Article
ISSN
1097-6833

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The epidermal growth factor (EGF) receptor mediates the effects of both EGF and transforming growth factor alpha (TGFalpha). Recent data suggested that EGF acts as a partial agonist/antagonist in hepatocytes, TGFalpha exerting a larger maximal stimulation of DNA synthesis than EGF. To further study