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Low potency inhibition of Ca2+ channel currents in human neuroblastoma (SH-SY5Y) cells by [Ala31]NPY, an l-alanine substituted analogue of neuropeptide Y

โœ Scribed by McDonald, R.L.; Beck-Sickinger, A.G.; Rist, B.; Vaughan, P.F.T.; Peers, C.


Book ID
123446859
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
342 KB
Volume
190
Category
Article
ISSN
0304-3940

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Enhancement of Ca2+channel currents in h
โœ Helen L. Reeve; Peter F. T. Vaughan; Chris Peers ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 985 KB

The effects of phorbol esters on Ca 2 + channel currents in human neuroblastoma SH-SY5Y cells were studied using whole-cell patch-clamp recordings. Bath application of 12-O-tetradecanoylphorbol-13-acetate (TPA) or phorbol 12, 13-dibutyrate (PDBu; 100 nM to 1 #M), known activators of protein kinase C