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Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells

✍ Scribed by Gianluca D'Ippolito; Sylma Diabira; Guy A. Howard; Bernard A. Roos; Paul C. Schiller


Book ID
116319668
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
470 KB
Volume
39
Category
Article
ISSN
8756-3282

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## Abstract Skeletal defects commonly suffer from poor oxygen microenvironments resulting from compromised vascularization associated with injury or disease. Adipose stem cells (ASCs) represent a promising cell population for stimulating skeletal repair by differentiating toward the osteogenic line