Low molecular weight protein tyrosine phosphatase genetic polymorphism and susceptibility to cancer development
β Scribed by I. Alho; M. Clara Bicho; R. Carvalho; A.P. da Silva; L. Costa; M. Bicho
- Book ID
- 113513283
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 193 KB
- Volume
- 181
- Category
- Article
- ISSN
- 0165-4608
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The energetics of substrate dephosphorylation in the low-molecularweight protein tyrosine phosphatase is studied with the empirical valence bond method in combination with molecular dynamics free energy perturbation simulations. Different mechanisms corresponding to different charge states of the re
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