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Low molecular weight chitosan is an efficient inhibitor of ribonucleases

โœ Scribed by Gennady I. Yakovlev; Vladimir A. Mitkevich; Nina K. Struminskaya; Valery P. Varlamov; Alexander A. Makarov


Book ID
116294634
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
205 KB
Volume
357
Category
Article
ISSN
0006-291X

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Pharmacokinetics, excretion, and metabolism of inogatran, a low-molecular-weight thrombin inhibitor, were studied in the rat, dog, and cynomolgus monkey. After intravenous administration the half-life was short in all three animal species, due to a small volume of distribution and a relatively high