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Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes

✍ Scribed by Amy R Peck, Agnieszka K Witkiewicz, Chengbao Liu, Alexander C Klimowicz, Ginger A Stringer, Edward Pequignot, Boris Freydin, Ning Yang, Adam Ertel, Thai H Tran, Melanie A Girondo, Anne L Rosenberg, Jeffrey A Hooke, Albert J Kovatich, Craig D Shriver, et al

Book ID: 118726957
Publisher: BioMed Central
Year: 2012
Tongue: English
Weight: 717 KB
Volume: 14
Category: Article
ISSN: 1465-5411
DOI: 10.1186/bcr3328

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✍ Claudio Dati; Roberto Muraca; Ornella Tazartes; Susanna Antoniotti; Isabelle Per 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 726 KB

c-erbB-2 and ras expression was measured on tumor extracts from 132 human primary breast carcinomas, by immunoblotting analysis. Expression of the c-erb8-2-encoded p I85 protein was observed in 39% of the samples and found to correlate with c-erbB-2 gene amplification, detected by Southern analysis