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Low levels of glucose transporters and( K^{ + }_{{ATP}} )channels in human pancreatic beta cells early in development

✍ Scribed by C. C. Richardson; K. Hussain; P. M. Jones; S. Persaud; K. Löbner; A. Boehm; A. Clark; M. R. Christie

Publisher
Springer
Year
2007
Tongue
English
Weight
344 KB
Volume
50
Category
Article
ISSN
0012-186X

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The present study demonstrates the action of the hypoglycaemic drugs repaglinide and glibenclamide in cultured newborn rat islet cells and mouse flTC3 cells. In cell-attached membrane patches of newborn rat islet cells repaglinide (10 nmol/ 1) and glibenclamide (20 nmol/1) decrease the open probabil