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Low Level of GABA in CSF in Vitamin B6-dependent Seizures

✍ Scribed by GERD KURLEMANN; E. MARIA MENGES; D. GEBHARD PALM


Book ID
115265855
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
157 KB
Volume
33
Category
Article
ISSN
0012-1622

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In an infant with neonatal seizures, CSF GABA levels were determined before and after treatment with vitamin B6. Before onset of treatment, the level of GABA in CSF was very low (13 pmol/ml). Injection of vitamin B6 blocked the seizures immediately. When GABA level in CSF was again analysed after co