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Low frequency of MECP2 mutations in mentally retarded males

✍ Scribed by Yntema, Helger G; Kleefstra, Tjitske; Oudakker, Astrid R; Romein, Tom; de Vries, Bert B A; Nillesen, Willy; Sistermans, Erik A; Brunner, Han G; Hamel, Ben C J; van Bokhoven, Hans


Book ID
110025257
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
76 KB
Volume
10
Category
Article
ISSN
1018-4813

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Among 243 institutionalized mentally retarded males in Japan, 13 patients (5.3%) with the fra(X)(q27) from nine families were detected. These 13 patients accounted for 8.6% of 152 male inmates with unknown causes of mental retardation in the population. One out of nine pedigrees had an apparently un