Low frequency of hCDC4 mutations in human primary ovarian cancer
β Scribed by A. Sgambato; V. Masciullo; M. Di Salvatore; P. Valdivieso; G. Bianchino; A. Zupa; G. Improta; C. Graziani; A. Rettino; R.A. Cifarelli; A. Cittadini; G. Scambia
- Book ID
- 113960987
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 173 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0090-8258
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The CDKNZ gene encodes a cell cycle regulatory protein and is located on chromosome 9 ~2 1 , a region deleted in a wide variety of primary tumours. While mutations in the CDKNZ gene itself are frequently observed in tumour cell lines, they are less common in primary turnouts. We have investigated th
The 185delAG and 5382insC founder mutations account for the majority of mutations identified in BRCA1 in Ashkenazi Jewish breast and breast-ovarian cancer families. Few non-founder BRCA1 mutations have been identified to date in these families. We initially screened a panel of 245 Ashkenazi Jewish b
## Abstract Several pathways have been implicated in the pathogenesis of endometrial carcinoma. Based on recent reports, __BRAF__ mutations provide an alternative route for activation of the RAS signalling pathway. The __CDKN2A (p16)__ tumour suppressor gene is also altered in several tumour types.