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Low Frequency of BRAF Mutations in Adult Patients with Papillary Thyroid Cancers Following Childhood Radiation Exposure

✍ Scribed by Collins, Barbara J.; Schneider, Arthur B.; Prinz, Richard A.; Xu, Xiulong


Book ID
120614983
Publisher
Mary Ann Liebert
Year
2006
Tongue
English
Weight
177 KB
Volume
16
Category
Article
ISSN
1050-7256

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## Abstract In papillary thyroid carcinogenesis, the constitutively activated mitogen‐activated protein (MAP) kinase signaling pathway caused by a genetic alteration such as __RET__/__PTC__ rearrangement or mutation of __RAS__ and __BRAF__ genes, is thought to be a major early event. Among these, t