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Low frequency mechanical stimulation inhibits adipogenic differentiation of C3H10T1/2 mesenchymal stem cells

โœ Scribed by Ghazaleh Khayat; Derek H. Rosenzweig; Thomas M. Quinn


Book ID
116409694
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
580 KB
Volume
83
Category
Article
ISSN
0301-4681

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The molecular mechanisms by which bone morphogenetic proteins (BMPs) promote skeletal cell differentiation were investigated in the murine mesenchymal stem cell line C3H10T1/2. Both BMP-7 and BMP-2 induced C3H10T1/2 cells to undergo a sequential pattern of chondrogenic followed by osteogenic differe