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Low doses of sarizotan reduce dyskinesias and maintain antiparkinsonian efficacy of l-Dopa in parkinsonian monkeys

✍ Scribed by Laurent Grégoire; Pershia Samadi; Julie Graham; Paul J. Bédard; Gerd D. Bartoszyk; Thérèse Di Paolo


Book ID
116820596
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
898 KB
Volume
15
Category
Article
ISSN
1353-8020

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Chronic treatment with small doses of ca
✍ Nancy Bélanger; Laurent Grégoire; Abdallah Hadj Tahar; Paul J. Bédard 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 94 KB

## Abstract Levodopa continues to be the most effective agent for the symptomatic treatment of Parkinson's disease (PD). But over time, initial benefits decline in efficacy because of a rise in adverse effects such as dyskinesias. The pathophysiology of levodopa‐induced dyskinesias (LID) is not com