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Low dose naltrexone administration in morphine dependent rats attenuates withdrawal-induced norepinephrine efflux in forebrain

✍ Scribed by Elisabeth J. Van Bockstaele; Yaping Qian; Robert C. Sterling; Michelle E. Page

Book ID: 116841280
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 808 KB
Volume: 32
Category: Article
ISSN: 0278-5846
DOI: 10.1016/j.pnpbp.2008.02.004

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## Abstract We previously described a decrease in withdrawal behaviors in opiate‐dependent rats that were chronically treated with very low doses of naltrexone in their drinking water. Attenuated expression of withdrawal behaviors correlated with decreased c‐Fos expression and intracellular signal