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Low dose etoposide (VP 16-213)/dexamethasone as salvage therapy in pretreated lymphoma

✍ Scribed by J. Weiß; H. H. Kirchner; H. Diedrich; S. Le Blane; E. Schmoll


Book ID
112785669
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
120 KB
Volume
111
Category
Article
ISSN
1432-1335

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Pre-treatment with low, non-toxic concentrations ( 0 . 0 4 ~~) of methotrexate (MTX) for I6 hr increased etoposide (VP 16)induced growth inhibition and cytotoxicity in the U937 human histiocytic lymphoma cell line. VP I6 cytotoxicity was significantly potentiated when the drug was given for 2 hr imm