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Low-density lipoprotein-apheresis in two patients with extremely elevated lipoprotein (a) levels

✍ Scribed by R. Bambauer; R. Schiel; J. Klinkmann; R. Latza

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 187 KB
Volume: 11
Category: Article
ISSN: 0733-2459
DOI: 10.1002/(sici)1098-1101(1996)11:2<78::aid-jca4>3.0.co;2-7

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✦ Synopsis

Two male Caucasian patients (36 and 42 years old) with heterozygous familial hypercholesterolemia and extremely elevated lipoprotein Lp(a) concentrations, resistant to diet and lipid-lowering drugs, were treated with low-density lipoprotein (LDL)-apheresis for 55 months (liposorber system, Kaneka@, Japan) and 15 months (immunoadsorption system, special Lp(a) columns, Lipopakm, Pocard, Russia). Lp(a) dropped on average by 50%, total cholesterol by 27%, LDL-cholesterol by 42%. triglycerides by 43%, and the fibrinogen concentration by 16%. o 1996 Wiley-Liss, lnc

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