Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma

Genome-wide high-resolution analysis of

Genome-wide high-resolution analysis of DNA copy number alterations in NF1-associated malignant peripheral nerve sheath tumors using 32K BAC array

✍ Kiran K. Mantripragada; Teresita Díaz de Ståhl; Chris Patridge; Uwe Menzel; Robi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 517 KB

## Abstract Neurofibromatosis Type I (NF1) is an autosomal dominant disorder characterized by the development of both benign and malignant tumors. The lifetime risk for developing a malignant peripheral nerve sheath tumor (MPNST) in NF1 patients is ∼10% with poor survival rates. To date, the molecu