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Low bone mineral density and bone mineral content are associated with low cobalamin status in adolescents

✍ Scribed by R. A. M. Dhonukshe-Rutten; M. van Dusseldorp; J. Schneede; L. C. P. G. M. de Groot; W. A. van Staveren


Publisher
Springer
Year
2004
Tongue
English
Weight
210 KB
Volume
44
Category
Article
ISSN
1436-6207

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Rare coding variants in ALPL are associa
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## Abstract Alkaline phosphatase (ALP) plays an essential role in the regulation of tissue mineralization, and its activity is highly heritable. Guided by genetic associations discovered in a murine model, we hypothesized a role for rare coding variants in determining serum ALP level and bone miner