𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Low-affinity peptides and T-cell selection

✍ Scribed by Andreas Ziegler; Claudia A. Müller; Rainer A. Böckmann; Barbara Uchanska-Ziegler


Book ID
116577981
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
543 KB
Volume
30
Category
Article
ISSN
1471-4906

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


A Reliable and Safe T Cell Repertoire ba
✍ H.A. VAN DEN BERG; D.A. RAND; N.J. BURROUGHS 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 505 KB

Antigens are presented to T cells as short peptides bound to MHC molecules on the surface of body cells. The binding between MHC/peptides and T cell receptors (TCRs) has a low affinity and is highly degenerate. Nevertheless, TCR-MHC/peptide recognition results in T cell activation of high specificit