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Lovastatin Retards the Progression of Established Glomerular Disease in Obese Zucker Rats

✍ Scribed by O'Donnell, Michael P.; Kasiske, Bertram L.; Kim, Youngki; Schmitz, Paul G.; Keane, William F.


Book ID
124147970
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
697 KB
Volume
22
Category
Article
ISSN
0272-6386

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## Abstract The combined use of lovastatin, a hypolipidemic agent effective in the reduction of cholesterol levels, and the lipophilic immunosuppressant, cyclosporine, was studied in the obese rat model. Pharmacokinetics, immunosuppressive activity, lipid levels, and creatinine clearances were comp