𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Lovastatin protects human neurons against Aβ-induced toxicity and causes activation of β-catenin–TCF/LEF signaling

✍ Scribed by Pradeep Salins; Salim Shawesh; Yang He; Alexander Dibrov; Tarek Kashour; Gilbert Arthur; Francis Amara

Book ID
116768919
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
906 KB
Volume
412
Category
Article
ISSN
0304-3940

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Different protection of K252a and N-acet
Different protection of K252a and N-acetyl-L-cysteine against amyloid-β peptide–induced cortical neuron apoptosis involving inhibition of MLK3–MKK7–JNK3 signal cascades
✍ Yan Xu; Xiao-Yu Hou; Yong Liu; Yan-Yan Zong 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

## Abstract Amyloid‐β peptide (Aβ) has been implicated in the etiopathogenesis of Alzheimer's disease (AD). However, the molecular mechanisms underlying Aβ neurotoxicity remain to be elucidated. This study showed that Aβ treatment resulted in the increased phosphorylation (activation) of MLK3, MKK7