Lovastatin inhibits adipogenic and stimulates osteogenic differentiation by suppressing PPARγ2 and increasing Cbfa1/Runx2 expression in bone marrow mesenchymal cell cultures

Ghrelin inhibits early osteogenic differ

Ghrelin inhibits early osteogenic differentiation of C3H10T1/2 cells by suppressing Runx2 expression and enhancing PPARγ and C/EBPα expression

✍ Sang Wan Kim; Ok Kyung Choi; Ju Yeon Jung; Jae-Yeon Yang; Sun Wook Cho; Chan Soo 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB

## Abstract Ghrelin is a 28‐residue peptide identified in the stomach as an endogenous ligand of the growth hormone secretagogue receptor that is expressed in a variety of peripheral tissues, as well as in the brain. In previous studies, ghrelin has been shown to stimulate both adipogenic different