Effect of cyclin E Overexpression on lov
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Paramita M. Ghosh; Marissa L. Moyer; Glen E. Mott; Jeffrey I. Kreisberg
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Article
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1999
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John Wiley and Sons
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English
โ 450 KB
๐ 2 views
The HMG-CoA reductase inhibitor, lovastatin, blocks targeting of the Rho and Ras families of small GTPases to their active sites by inhibiting protein prenylation. Control NIH3T3 cells, and those overexpressing human cyclin E protein were treated with lovastatin for 24 h to determine the effects of