𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Loss of type III transforming growth factor-β receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma

✍ Scribed by Cooper, S J; Zou, H; LeGrand, S N; Marlow, L A; von Roemeling, C A; Radisky, D C; Wu, K J; Hempel, N; Margulis, V; Tun, H W


Book ID
109972752
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
738 KB
Volume
29
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Reduction of transforming growth factor-
✍ Hirotaka Fukasawa; Tatsuo Yamamoto; Yoshihide Fujigaki; Taro Misaki; Naro Ohashi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 757 KB

## Abstract Although dysregulation of transforming growth factor‐β (TGF‐β) signaling is implicated in renal carcinogenesis, its precise mechanism is unknown in renal cell carcinoma (RCC). In our study, we investigated Smad‐mediated TGF‐β signaling pathway and its regulatory mechanisms in surgical s

Growth inhibition due to complementation
✍ Yasunori Miyafuji; Xiaoling Zhong; Iichiro Uchida; Minoru Koi; Hiromichi Hemmi 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 257 KB

The transforming growth-beta receptor type II (TGF-beta RII) gene is one of the target genes of the DNA mismatch repair (MMR) defect. The human colorectal carcinoma cell line HCT116 has mutations in the hMLH1 gene and in the microsatellite region of the TGF-beta RII gene, both located on the short a

Novel microdeletion in the transforming
✍ Jiu-Cun Wang; Cheng-Chang Su; Ji-Bin Xu; Le-Zhen Chen; Xiao-Hua Hu; Gui-Ying Wan 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 386 KB 👁 1 views

## Abstract Mutations in the tumor suppressor gene transforming growth factor β (TGFB) Type II receptor (__TGFBR2__) are frequently found in many cancers with microsatellite instability, but are less common in lung cancer. In the present study, we looked for mutations in __TGFBR2__ in nonsmall cell