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Loss of TNF-α-regulated COX-2 expression in ovarian cancer cells

✍ Scribed by Yang, Wan-Lin; Roland, Isabelle H; Godwin, Andrew K; Xu, Xiang-Xi

Book ID
110069981
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
524 KB
Volume
24
Category
Article
ISSN
0950-9232

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## Abstract The pro‐inflammatory cytokine, tumour necrosis factor‐α, TNF‐α, is dysregulated in malignant compared with normal ovarian surface epithelium (OSE). Several epidemiological studies have associated inflammation with ovarian tumorigenesis, with TNF‐α playing a key role in modulating invasi