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Loss of the DEK-CAN fusion transcript in a child with t(6;9) acute myeloid leukemia following chemotherapy and allogeneic bone marrow transplantation

โœ Scribed by Boer, J; Mahmoud, H; Raimondi, S; Grosveld, G; Krance, R


Book ID
110053413
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
51 KB
Volume
11
Category
Article
ISSN
0887-6924

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The t(6;9) associated with a subtype of acute myeloid leukemia (AML) was shown t o generate a fusion between the 3' part of the CAN gene on chromosome 9 and the 5' part of the DEK gene on chromosome 6. The same part of the CAN gene appeared t o be involved in a case of acute undifferentiated leukemi